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How it works

What is DCT and how does it work?

Dendritic Cell Therapy (DCT) is a form of immunotherapy. Like other immunotherapeutic approaches, its goal is to support the body’s immune system in recognising structures associated with cancer cells and initiating an immune response.

Conventional immunotherapy drugs often target shared tumour markers or common genetic mutations found in certain types of cancer. However, many patients have tumours with rare or highly individualised molecular characteristics that are not addressed by standard therapies currently available on the market.

DCT offers a more personalised approach: using a patient’s own immune cells, dendritic cells are processed in our own GMP-certified laboratory and exposed to tumour - associated information derived from the patient’s own sample. This allows the development of a cell-based therapy tailored to the individual tumour profile and may provide an immunotherapeutic option also for patients with less common cancer types.

Each treatment is individualised, and potential effects depend on various factors such as tumour type, disease stage, and the patient’s immune status. We would be happy to advise you in a personal consultation.

LDG Shorts

Frank Gansauge gives an overview of the DCT process.

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Could DCT work for me?

Dendritic Cell Therapy (DCT) is a personalised and well-tolerated form of immunotherapy that may be considered for patients with various types of cancer and across different age groups.

Discuss it with us
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How it works

Tailored Immunotherapy.

Dendritic Cell Therapy (DCT) is an advanced immunotherapy designed to help your immune system recognise features unique to your tumour.

In our certified lab, we isolate immune cells from a small blood sample and process them to generate dendritic cells exposed to tumour-specific markers. After several days, these cells are returned to your bloodstream. This approach aims to support your immune system to detect and target previously unrecognised cancer-related markers.

3 Steps Infographic

Step 1

Consultation with Professor Gansauge in Berg. Blood is taken and a vitamin infusion is given. (approx. 2.5 hours)

Step 2

In our laboratory, dendritic cells are matured after being exposed to cancer-specific markers derived from your blood sample.

Step 3

The mature dendritic cells are administered through a simple injection into the skin of the abdominal area. This is typically followed by a supportive vitamin infusion. (approx. 2 hours)

Step 1

Consultation with Professor Gansauge in Berg. Blood is taken and a vitamin infusion is given. (approx. 2.5 hours)

Step 2

In our laboratory, dendritic cells are matured after being exposed to cancer-specific markers derived from your blood sample.

Step 3

The mature dendritic cells are administered through a simple injection into the skin of the abdominal area. This is typically followed by a supportive vitamin infusion. (approx. 2 hours)

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Speaking to Frank at the time, he said that, you know, it's very difficult to ascertain exactly what the impact of the dendritic cell therapy is, especially when you're doing it with chemotherapy, because he can't tell you exactly what's doing what. But I did have a period of nearly three months when I wasn't on chemo, as it was before and after, you know, removal of the main tumor. And actually, the, uh, tumors here in my neck over that period, which had been growing quite significantly, actually reduced in size. So, I have evidence that DCT by itself was having an impact at that time. And then I went to second line of treatment, which is polfiri, which Imuranotecan. And so that started in, around about June last year. And I think this is, uh, in my personal opinion due to DCT, is that I've then had a very good response on the third round, third round of three months that is. And I had a scan which was no evidence of disease. Nothing. Which was really not expected. The oncologist didn't really believe it, so I had a PET scan, uh, two weeks later, uh, but that also confirmed that I was indeed tumor free, or I am indeed tumor free. And since then I've had another three month treatment, uh, of chemotherapy, and a subsequent scan, and that's also come up as no evidence of disease as well. So, I think DCT and LDG have definitely contributed to the good result that I've had so far."},{"@type": "VideoObject","name": "Meet Wendy","description": "I feel DCT has had an impact for me… the first time I came my scan showed that my cancer had shrunk and since then it’s been stable","thumbnailUrl": "https://dendriticcelltherapybyldg.co.uk/cmsUploads/testimonials/images/thumbs/wendy_testimonial_screenshot-1.jpg","embedUrl": "https://vimeo.com/1052106281","@id": "https://vimeo.com/1052106281","transcript": "So, my DC journey, I first got diagnosed with cancer, breast cancer, in 2020, and I had an operation and treatment and that-- and that. And then I was fine for two years, and then it g- it spread in my bones. So, I s- my... Actually, my employer researched this just for alternative treatments to see what we would come up with, and we came across Frank's treatment. So, we done our research and we got all the certificates and everything, and we just said we would try it. We, we took a, a chance on it. And I feel DCT has had an impact for me. Um, the first time I came, when I went back home, my scans, it... My cancer had shrunk, and since then it has stayed stable. So, I have come back over again to test it again to see when I go back in three months if it has, uh, shrunk more, and I feel great. I don't feel like there's anything wrong with me. And as long as that I keep feeling like that, I will keep coming back to get it done."},{"@type": "VideoObject","name": "Meet Matt","description": "What works for me may not work for everyone but it did [work for me] and I’m very excited about that.","thumbnailUrl": "https://dendriticcelltherapybyldg.co.uk/cmsUploads/testimonials/images/thumbs/matt_testimonial_screenshot.jpg","embedUrl": "https://vimeo.com/1052108361","@id": "https://vimeo.com/1052108361","transcript": "So the background of my DC treatment was that I was diagnosed with glioblastoma, which is a brain cancer, in December '21. And I had surgery as standard of care, which includes radio and chemo, and that went through to early '22. But then it came back, and it was that point I came to Dr. Frank and his clinic looking for quite simply the latest and the most leading-edge stuff that I could find and that I was eligible for. Using that, I had a couple treatments here, and the first treatment was in combination with chemo, and that showed a shrinkage of the tumor. I then followed that up with another chemo and another shot of DCT, and on that, I recently had a cleaned MRI of my brain. Now, this is extremely good, but let's be clear. As I say, everybody grows their own. What works for me may not work for everyone, but it did, and I am very, very excited about that."}]}}

Testimonials

Patient Stories

Learn about the experience had by some of our previous patients..

Meet Matt

“What works for me may not work for everyone but it did [work for me] and I’m very excited about that.”

Watch the Video
Meet Wendy

“I feel DCT has had an impact for me… the first time I came my scan showed that my cancer had shrunk and since then it’s been stable”

Watch the Video
Meet Ben

“I think [that] DCT and LDG have definitely contributed to the good result that I have had so far.”

Watch the Video
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